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cbclark4
Joined: 20 Aug 2006
Location: Masan
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 Posted: Thu Oct 04, 2007 9:08 pm Post subject: |
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So why ban thalidomide, it's cheap it does what it's supposed.
Are the big drug companies behind it, for profit?
Can you smell the sarcasm? |
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mindmetoo
Joined: 02 Feb 2004
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| Posted: Fri Oct 05, 2007 3:21 am Post subject: |
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| cbclark4 wrote: |
So why ban thalidomide, it's cheap it does what it's supposed.
Are the big drug companies behind it, for profit?
Can you smell the sarcasm? |
| Quote: |
FDA Approval
"On May 26, 2006, the U.S. Food and Drug Administration granted accelerated approval for thalidomide (Thalomid, Celgene Corporation) in combination with dexamethasone for the treatment of newly diagnosed multiple myeloma (MM) patients." [2] The FDA approval came seven years after the first reports of efficacy in the medical literature (Desikan R, Munshi N, Zeldis J, et al. Activity of thalidomide (THAL) in multiple myeloma (MM) confirmed in 180 patients with advanced disease. Blood 1999;94:Suppl 1:603a-603a.abstract), and Celgene took advantage of "off-label" marketing opportunities to promote the drug in advance of its FDA approval for the myeloma indication. Thalomid, as the drug is commercially known, sold over $300 million per year, while only approved for leprosy. [3] Thalidomide was and still is (2006) an important advance in the treatment of multiple myeloma, ever since news of its efficacy spread throughout the medical literature in 2000. [citation needed] The drug has some bothersome nuisance side effects such as neuropathy, constipation and fatigue, but is likely more effective than standard chemotherapy for multiple myeloma. Thalidomide, along with another new drug, bortezomib, is changing the landscape of multiple myeloma treatment, such that toxic stem cell transplants may no longer be the standard treatment for this incurable malignancy. |
I'm not sure where you're going with this c. But both seem victims of their past and still have a lot of bad PR although they can used for good, if applied properly. It's a bit like uranium. We can power a city or blow up a city. |
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