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ontheway
Joined: 24 Aug 2005 Location: Somewhere under the rainbow...
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Posted: Tue Aug 25, 2009 8:18 am Post subject: You'd Be Smart If You Weren't So Fat ... |
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Obese People Have 'Severe Brain Degeneration'
LiveScience.com livescience Staff
livescience.com � 1 hr 38 mins ago
A new study finds obese people have 8 percent less brain tissue than normal-weight individuals. Their brains look 16 years older than the brains of lean individuals, researchers said today.
Those classified as overweight have 4 percent less brain tissue and their brains appear to have aged prematurely by 8 years.
The results, based on brain scans of 94 people in their 70s, represent "severe brain degeneration," said Paul Thompson, senior author of the study and a UCLA professor of neurology.
"That's a big loss of tissue and it depletes your cognitive reserves, putting you at much greater risk of Alzheimer's and other diseases that attack the brain," said Thompson. "But you can greatly reduce your risk for Alzheimer's, if you can eat healthily and keep your weight under control."
The findings are detailed in the online edition of the journal Human Brain Mapping.
Obesity packs many negative health effects, including increased risk of heart disease, Type 2 diabetes, hypertension and some cancers. It's also been shown to reduce sexual activity.
More than 300 million worldwide are now classified as obese, according to the World Health Organization. Another billion are overweight. The main cause, experts say: bad diet, including an increased reliance on highly processed foods.
Obese people had lost brain tissue in the frontal and temporal lobes, areas of the brain critical for planning and memory, and in the anterior cingulate gyrus (attention and executive functions), hippocampus (long-term memory) and basal ganglia (movement), the researchers said in a statement today. Overweight people showed brain loss in the basal ganglia, the corona radiata, white matter comprised of axons, and the parietal lobe (sensory lobe).
"The brains of obese people looked 16 years older than the brains of those who were lean, and in overweight people looked 8 years older," Thompson said.
Obesity is measured by body mass index (BMI), defined as the weight in kilograms divided by the square of the height in meters. A BMI over 25 is defined as overweight, and a BMI of over 30 as obese.
The research was funded by the National Institute on Aging, National Institute of Biomedical Imaging and Bioengineering, National Center for Research Resources, and the American Heart Association. |
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mises
Joined: 05 Nov 2007 Location: retired
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Posted: Tue Aug 25, 2009 9:00 am Post subject: |
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Obesity and Vit D.
http://www.ncbi.nlm.nih.gov/pubmed/19054627?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DiscoveryPanel.Pubmed_RVAbstractPlus
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Common obesity is associated with the metabolic syndrome and can be distinguished from secondary obesity and from rare forms of monogenic and polygenic obesity. The prevalence of common obesity has become a public health concern in many countries as phenomenological approaches to the understanding of obesity have failed to achieve any long term effect on prevention or treatment. There is evidence for a central control mechanism which maintains body-weight to a set-point by the regulation of energy intake and energy expenditure through homeostatic pathways. It is suggested in this paper that common obesity occurs when the set-point is raised and that accumulation of fat mass functions to increase body size. Larger body size confers a survival advantage in the cold ambient temperatures and food scarcity of the winter climate by reducing surface area to volume ratio and by providing an energy store in the form of fat mass. In addition, it is suggested that the phenotypic metabolic and physiological changes observed as the metabolic syndrome, including hypertension and insulin resistance, could result from a winter metabolism which increases thermogenic capacity. Common obesity and the metabolic syndrome may therefore result from an anomalous adaptive winter response. The stimulus for the winter response is proposed to be a fall in vitamin D. The synthesis of vitamin D is dependent upon the absorption of radiation in the ultraviolet-B range of sunlight. At ground level at mid-latitudes, UV-B radiation falls in the autumn and becomes negligible in winter. It has previously been proposed that vitamin D evolved in primitive organisms as a UV-B sensitive photoreceptor with the function of signaling changes in sunlight intensity. It is here proposed that a fall in vitamin D in the form of circulating calcidiol is the stimulus for the winter response, which consists of an accumulation of fat mass (obesity) and the induction of a winter metabolism (the metabolic syndrome). Vitamin D deficiency can account for the secular trends in the prevalence of obesity and for individual differences in its onset and severity. It may be possible to reverse the increasing prevalence of obesity by improving vitamin D status. |
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Fox

Joined: 04 Mar 2009
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Posted: Tue Aug 25, 2009 4:33 pm Post subject: |
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Wow, that's a much scarier side effect of being overweight than I've heard to date. For some reason, I don't find things like higher risk of heart disease particularly scary, but losing brain tissue seems terrifying!
True or false, in all honesty this study has probably scared me into watching my weight for the rest of my life. |
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bacasper

Joined: 26 Mar 2007
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Posted: Tue Aug 25, 2009 7:32 pm Post subject: |
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It gives new meaning to the term "fathead." |
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mises
Joined: 05 Nov 2007 Location: retired
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Posted: Tue Aug 25, 2009 7:38 pm Post subject: |
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But we all knew this, right? I'm not the only one who isn't surprised, I'm sure. |
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Fox

Joined: 04 Mar 2009
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Posted: Tue Aug 25, 2009 7:40 pm Post subject: |
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mises wrote: |
But we all knew this, right? |
You knew that a life-time of being obese prematurely aged your brain by 16 years and caused an 8% loss of tissue? |
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mises
Joined: 05 Nov 2007 Location: retired
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Posted: Tue Aug 25, 2009 7:51 pm Post subject: |
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Fox wrote: |
mises wrote: |
But we all knew this, right? |
You knew that a life-time of being obese prematurely aged your brain by 16 years and caused an 8% loss of tissue? |
No, not specifically that. But the study does not surprise me and supports my assumptions about the obese and their inner-workings. |
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djsmnc

Joined: 20 Jan 2003 Location: Dave's ESL Cafe
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Posted: Tue Aug 25, 2009 8:27 pm Post subject: |
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I've been waiting so long for justification to use the "fat and dumb" insult. I knew there was a connection. KNEW IT! Sometimes science just seems to clarify the obvious. |
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Steelrails

Joined: 12 Mar 2009 Location: Earth, Solar System
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Posted: Tue Aug 25, 2009 8:44 pm Post subject: |
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Funny, I thought Homer was obese because he was dumb...now I found out he's dumb because he's obese.
Given our reps in Congress are so overweight, it dosen't suprise me with the results we get.
Then again W Bush was pretty lean. |
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Koveras
Joined: 09 Oct 2008
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Posted: Tue Aug 25, 2009 10:13 pm Post subject: |
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The question is, how do I get my parents to read this study without implying that they're fat and old and stupid? |
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DWAEJIMORIGUKBAP
Joined: 28 May 2009 Location: Electron cloud
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Posted: Tue Aug 25, 2009 11:12 pm Post subject: |
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The question is should I stop eating a mozzerella cheese stick with my breakfast every day now...? |
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Fox

Joined: 04 Mar 2009
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Posted: Tue Aug 25, 2009 11:22 pm Post subject: |
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Koveras wrote: |
The question is, how do I get my parents to read this study without implying that they're fat and old and stupid? |
Surely they must have fat, old, and stupid friends. Suggest they read it so they can make a reasoned appeal to their friends. |
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bacasper

Joined: 26 Mar 2007
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Posted: Wed Aug 26, 2009 2:54 am Post subject: |
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djsmnc wrote: |
I've been waiting so long for justification to use the "fat and dumb" insult. I knew there was a connection. KNEW IT! Sometimes science just seems to clarify the obvious. |
Isn't America the most obese country in the world?
Cubanos and Norks ought to be geniuses. |
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Steelrails

Joined: 12 Mar 2009 Location: Earth, Solar System
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Posted: Wed Aug 26, 2009 5:52 am Post subject: |
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bacasper wrote: |
djsmnc wrote: |
I've been waiting so long for justification to use the "fat and dumb" insult. I knew there was a connection. KNEW IT! Sometimes science just seems to clarify the obvious. |
Isn't America the most obese country in the world?
Cubanos and Norks ought to be geniuses. |
Ahhh but the fellers in charge are all a little hefty- KJI, Raul, and Fidel all look a little pudgy. |
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