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Donate your CPU time to a worthy cause: Folding At Home

 
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gsxr750r



Joined: 29 Jan 2007

PostPosted: Sun Apr 01, 2007 5:22 pm    Post subject: Donate your CPU time to a worthy cause: Folding At Home Reply with quote

Please check out this site:

http://folding.stanford.edu/


Our goal: to understand protein folding, misfolding, and related diseases

What is protein folding and how is folding linked to disease? Proteins are biology's workhorses -- its "nanomachines." Before proteins can carry out these important functions, they assemble themselves, or "fold." The process of protein folding, while critical and fundamental to virtually all of biology, in many ways remains a mystery.

Moreover, when proteins do not fold correctly (i.e. "misfold"), there can be serious consequences, including many well known diseases, such as Alzheimer's, Mad Cow (BSE), CJD, ALS, Huntington's, Parkinson's disease, and many Cancers and cancer-related syndromes.

You can help by simply running a piece of software. Folding@Home is a distributed computing project -- people from through out the world download and run software to band together to make one of the largest supercomputers in the world. Every computer makes the project closer to our goals.

Folding@Home uses novel computational methods coupled to distributed computing, to simulate problems thousands to millions of times more challenging than previously achieved.





목표: 단백질 접힘, 단백질 뭉침 및 그와 관련된 질병 연구

http://folding.stanford.edu/korea/


단백질이란 무엇이며 단백질은 왜 고유의 모양으로 "접히게"되는가? 단백질은 생체 내에 존재하는 나노미터 규모의 작지만, 매우 유용한 일꾼들이다. 단백질이 고유한 작용을 하기 위해서는 먼저 그 단백질 고유의 모양으로 "접혀야 (fold)" 한다. 이런 접힘의 과정은 그 기본적인 중요성에 비해 아직 알려진 것이 그다지 많지 않다. 뿐만 아니라, (어쩌면 그다지 놀랍지 않은 일이지만) 단백질이 정상적인 모양으로 접히지 않는 경우 (misfolding) 심각한 결과, 즉 많은 질병들을 초래하기도 한다. 치매(Alzheimer's disease), 광우병, 파킨슨씨 병등이 이런 잘못된 접힘과 관련되어 있음은 이미 밝혀진바 있다.

Folding@Home은 어떤 일을 하는가? Folding@Home은 분산계산 프로젝트로, 위에서 설명한 단백질 접힘, 잘못된 접힘, 단백질 뭉침, 또는 이들과 관련된 질병들을 연구하고 있다. 대규모의 분산 계산은 최근 도입된 새로운 기법이며, 이 기법을 통해 Folding@Home에서는 종전에 사용된 방법들에 비해 수천 또는 수백만 배의 거대한 규모의 계산을 수행하고 있다. 이 방법으로 Folding@Home연구팀은 세계 최초로 직접적인 단백질 접힘을 이론적으로 관찰하였으며, 이를 관련된 질병 연구에 적용하려 하고 있다..


Folding@Home 에서 얻어진 villin 계산의 결과


참여 방법: 사용자들은 Folding@Home 프로그램을 다운로드 받아 실행함으로써 프로젝트에 참여할 수 있습니다. 기본적으로 프로그램 사용자가 많으면 많을수록 프로젝트의 수행속도가 빨라지게 되며, 기본적으로 전체 프로젝트는 많은 사용자들의 자발적인 참여에 의존하고 있습니다.

지금까지의 결과는? 현재까지 몇가지 연구 성과를 가져왔습니다. 자세한 사항은 관련과학, 연구결과 또는 발표 논문 링크에 설명되어 있습니다.
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eamo



Joined: 08 Mar 2003
Location: Shepherd's Bush, 1964.

PostPosted: Sun Apr 01, 2007 7:20 pm    Post subject: Reply with quote

That looks like a great way to give something very easily GSX.....

I'm giving all my idle processing power to SETI@home. Been doing so for 5 years.

You can download the BOINC client which can switch research projects on your computer. There are many projects to choose so you pick the ones you're interested in and allocate a certain percentage of your processor time to each.

http://boinc.berkeley.edu/ Download here.

Lot's of worthy causes for medicine and stuff.

Be warned. If you don't think your computer has very good cooling then set the limit in BOINC preferences for processor time to about 50%. Using 100% of your processor all the time will seriously overheat poorly vented computers.
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ttompatz



Joined: 05 Sep 2005
Location: Kwangju, South Korea

PostPosted: Sun Apr 01, 2007 8:10 pm    Post subject: Reply with quote

eamo wrote:
That looks like a great way to give something very easily GSX.....

I'm giving all my idle processing power to SETI@home. Been doing so for 5 years.

You can download the BOINC client which can switch research projects on your computer. There are many projects to choose so you pick the ones you're interested in and allocate a certain percentage of your processor time to each.

http://boinc.berkeley.edu/ Download here.

Lot's of worthy causes for medicine and stuff.

Be warned. If you don't think your computer has very good cooling then set the limit in BOINC preferences for processor time to about 50%. Using 100% of your processor all the time will seriously overheat poorly vented computers.


I have also been crunching for SETI for a while (since may 2000).

I haven't cooked a processor yet but they do get warm (average 10C degrees above when it is turned off).

I do run mine at 100%.
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bellum99



Joined: 23 Jan 2003
Location: don't need to know

PostPosted: Tue Apr 03, 2007 2:03 am    Post subject: Reply with quote

Everyone should help SETI. I have been doing it for a long time,too.
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gsxr750r



Joined: 29 Jan 2007

PostPosted: Tue Apr 03, 2007 2:54 am    Post subject: Reply with quote

I've set up about 10 computers at work to do folding at medium levels when not in use by anyone else. Also ran the PS3 some, and completed one work unit overnight.

As a comparison, it seems to take two days to complete a work unit running 100% CPU on computer, whereas the PS3 does it in about 7 hours.
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