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asmith
Joined: 18 Jun 2009
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 Posted: Sat Oct 31, 2009 7:44 pm Post subject: The Wonders of Tamiflu |
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I recently caught seasonal flu. I was sent home from my school due to a high fever.
I took Tamiflu for a few days. Never felt better. |
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Yesterday
Joined: 15 Aug 2003
Location: Land of the Morning DongChim (Kancho)
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| Posted: Sat Oct 31, 2009 7:48 pm Post subject: Re: The Wonders of Tamiflu |
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| asmith wrote: |
I recently caught seasonal flu. I was sent home from my school due to a high fever.
I took Tamiflu for a few days. Never felt better. |
Take it at your own risk - especially if you have a history of "depression"
Common adverse drug reactions (ADRs) associated with oseltamivir (Tamiflu) include: nausea, vomiting, diarrhea, abdominal pain, and headache. Rare ADRs include: hepatitis and elevated liver enzymes, rash, allergic reactions including anaphylaxis, and Stevens-Johnson syndrome.
Various other ADRs have been reported in postmarketing surveillance including: toxic epidermal necrolysis, cardiac arrhythmia, seizure, confusion, aggravation of diabetes, and haemorrhagic colitis.
There are concerns that oseltamivir may cause dangerous psychological, neuropsychiatric side effects including self harm in some users. These dangerous side effects occur more commonly in children than in adults.
This stems from cases in Japan, where the drug is most heavily prescribed, consuming 60% of the world's production. Concern has focused on teenagers, but problems have also been reported in children and adults.
In March 2007, Japan's Health Ministry warned that oseltamivir should not be given to those aged 10 to 19. The Ministry had previously decided, in May 2004, to change the literature accompanying oseltamivir to include neurological and psychological disorders as possible adverse effects, including: impaired consciousness, abnormal behavior, and hallucinations.
According to Japan's Health Ministry, between 2004 and March 2007, fifteen people aged 10 to 19 have been injured or killed by jumps or fallen from buildings after taking oseltamivir, and one 17-year-old died after he jumped in front of a truck.
A renewed investigation of the Japanese data was completed in April 2007. It found that 128 patients had been reported to behave abnormally after taking oseltamivir since 2001. Forty-three of them were under 10 years old, 57 patients were aged 10 to 19, and 28 patients were aged 20 or over. Eight people, including five teens and three adults, had died from these actions.
In October 2006, Shumpei Yokota, a professor of pediatrics at Yokahama City University, released the results of research involving around 2,800 children which found no difference in the behavior between those who took oseltamivir and those who did not. Chugai Pharmaceutical Co. (which produces oseltamivir in Japan) gave Yokota's department 10 million yen (about US$105,000) over five years.
To determine whether to lift the 2007 ban, a research team from the Japanese Health, Labour and Welfare Ministry studied 10,000 children under the age of 18 who had been diagnosed with influenza since 2006. The study was finalised in April 2009. Taking into account all degrees of abnormal behaviour, including minor behavioural problems such as incoherent speech, the study found that children who took oseltamivir were 54 percent more likely to exhibit abnormal behaviour than those who did not take the drug. When the team limited its analysis to children who had displayed serious abnormal behaviour that led to injury or death, it found those who had taken oseltamivir were 25 per cent more likely to behave unusually.
In November 2006, the United States Food and Drug Administration (FDA) amended the warning label to include the possible side effects of delirium, hallucinations, or other related behavior. This went further than the FDA's previous pronouncement, from a year before, that there was insufficient evidence to claim a causal link between oseltamivir use and the deaths of 12 Japanese children (only two were from neurological problems, although more have died since then).
The change to a more cautionary stance was attributed to 103 new reports that the FDA received of delirium, hallucinations and other unusual psychiatric behavior, mostly involving Japanese patients, received between August 29, 2005 and July 6, 2006. This was an increase from the 126 similar cases logged between the drug's approval in 1999 and August 2005.
Roche points out that oseltamivir has been used to treat over 50 million people since 1999, and states that influenza may itself cause psychological problems.
In March 2007, the European Medicines Agency said that the benefits of oseltamivir outweighed the costs, but that it would closely monitor reports from Japan.
In April 2007, South Korea issued a safety warning against prescribing oseltamivir to teenagers except in special cases
http://en.wikipedia.org/wiki/Oseltamivir
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crossmr
Joined: 22 Nov 2008
Location: Hwayangdong, Seoul
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| Posted: Sat Oct 31, 2009 9:00 pm Post subject: |
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*yawn*
if you read the info pamphlets on most drugs it will scare the crap out of you. Tamiflu is no different.
For me, I need to make sure I take it on a full stomach. Taking it on a half-empty stomach makes me feel pretty messed up. |
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dalem
Joined: 30 Dec 2008
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| Posted: Sat Oct 31, 2009 9:59 pm Post subject: |
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| my boyfriend took it and felt really bad nausea the rest of the day. However, i am uncertain if he took it on an empty stomach. |
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Rteacher
Joined: 23 May 2005
Location: Western MA, USA
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| Posted: Mon Nov 02, 2009 5:01 am Post subject: |
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| My Korean co-teacher said that she felt very sick from flu last week but shortly after taking Tamiflu her fever went down and she felt much better. She said that no other treatments or shots she's gotten were effective at all, but Tamiflu seems to work great. |
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Forward Observer
Joined: 13 Jan 2009
Location: FOB Gloria
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| Posted: Mon Nov 02, 2009 5:36 am Post subject: |
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| Don't you need a prescription for it? |
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dalem
Joined: 30 Dec 2008
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| Posted: Mon Nov 02, 2009 5:39 am Post subject: |
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| i don't believe so? my boss got paranoid about swine flu over semester break and had us all taking preventative tamiflu (her idea, not ours. not sure if it even works that way). None of us had perscriptions but she was passing it out like candy. |
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crossmr
Joined: 22 Nov 2008
Location: Hwayangdong, Seoul
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| Posted: Mon Nov 02, 2009 5:39 am Post subject: |
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| Forward Observer wrote: |
| Don't you need a prescription for it? |
Usually but last week they announced you could buy it over the counter. |
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egrog1717
Joined: 12 Mar 2008
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| Posted: Mon Nov 02, 2009 3:53 pm Post subject: |
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| dalem wrote: |
| i don't believe so? my boss got paranoid about swine flu over semester break and had us all taking preventative tamiflu (her idea, not ours. not sure if it even works that way). None of us had perscriptions but she was passing it out like candy. |
Repeat after me: "I am not a slave.... I am not a slave... I am not a slave..."
Sorry... Just seems crazy to me that someone would take medication because their boss told them to... |
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Cerulean
Joined: 19 Aug 2009
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| Posted: Mon Nov 02, 2009 4:22 pm Post subject: |
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egrog1717,
I agree with you. I may give my boss the idea that I took something that he/she gave me but I wouldn't actually swallow it. |
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Yaya
Joined: 25 Feb 2003
Location: Seoul
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| Posted: Mon Nov 02, 2009 6:24 pm Post subject: |
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| crossmr wrote: |
| Forward Observer wrote: |
| Don't you need a prescription for it? |
Usually but last week they announced you could buy it over the counter. |
I just went to a pharmacy and they said I DO need a prescription. |
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crossmr
Joined: 22 Nov 2008
Location: Hwayangdong, Seoul
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| Posted: Mon Nov 02, 2009 6:37 pm Post subject: |
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| Yaya wrote: |
I just went to a pharmacy and they said I DO need a prescription. |
You can search the forums for the thread. There was an article on it or something. Are you Korean or gyopo? if not ask a K friend to see if they'll give it to them.
I had a prescription for mine, just going on what that article said last week.
found it:
http://forums.eslcafe.com/korea/viewtopic.php?t=169473
I guess it doesn't say without a prescription, but I assume tamiflu was available at drug stores already with a prescription prior to that day. |
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mayorgc
Joined: 19 Oct 2008
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| Posted: Mon Nov 02, 2009 7:27 pm Post subject: |
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| I'm pretty sure you need a prescription to get tamiflu at the pharmacy. That's what I've been told. |
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aussieb
Joined: 08 Sep 2007
Location: Brisbane,Australia
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| Posted: Mon Nov 02, 2009 9:53 pm Post subject: |
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| Interesting read "Yesterday". It almost sounds like a Japanese equivalent of Fan Death. |
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Yaya
Joined: 25 Feb 2003
Location: Seoul
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| Posted: Mon Nov 02, 2009 9:56 pm Post subject: |
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| mayorgc wrote: |
| I'm pretty sure you need a prescription to get tamiflu at the pharmacy. That's what I've been told. |
Yep, unless you know the pharmacist or something, you NEED a prescription. |
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